Semaglutide to reduce carb-counting burden on closed loop
What this study tests
McGill randomized placebo-controlled 2×3 factorial crossover trial of weekly semaglutide and meal strategies in adults with established T1D using advanced AID. The primary endpoint compares daytime glucose time in range on semaglutide versus placebo; this is not a beta-cell regeneration trial.
Editorial review: .
Registry checked: 2026-09-17. Registry’s own update: 2024-12-18.
Source dates appear in the references where available; this record has no dated citation metadata.
Trial status, labels and access can change between reviews. How we review the evidence · How to read the evidence
Evidence at a glance
- Who can enter the study?
- Adults with T1D for at least one year and at least three months of commercial advanced AID use; effective contraception is required for participants with child-bearing potential. See registry for full exclusions. Registered eligibility ↗Enrollment criteria describe who may enter. They do not establish who was analyzed or the denominator for a reported result.
- Reported benefit and results
- No results posted yet.Read the result sources and their limitations →
- Important harms
- Read the reported results, safety discussion and original sources. A separate harms summary is not available; this does not establish safety.
- Research access and approval
- Study regions: Canada. A trial listing does not establish product approval or current recruitment at a particular site. Check the study’s current entry requirements.
- What remains uncertain?
- Read the full discussion and original sources for study limitations. Planned endpoints and completion dates are not results.
Research status alone does not establish approval, clinical benefit or local availability.
Primary endpoints
- Daytime glucose time in range for semaglutide versus placebo
The full picture
This record has no longer discussion. Use the study criteria, reported results and original sources on this page to assess what is known and what remains unresolved.
Sources
- [1]